Previously Completed Studies
- June 2009 - Present
-
Sternal Plating Study (Biomet)
- June 2005 - Present
- The HeartMate II LVAS Pivotal Study (Thoratec) Destination therapy
- February 1991 – June 1995
- Clinical Investigation of the Excel – VR Pulse
Generator (Cardiac Pacemakers, Inc.)
- July 1991 – May 1995
- Comparison of the Hemodynamic Performance of Direct
Cardiomyoplasty in an Intracoronary Adriamycin Induced Animal Model of Congestive
Heart Failure (Baptist Memorial Healthcare Foundation)
- March 1994 – January 2000
- Early Thrombosis of Arterialized Vein Grafts and
Its Effect on Endothelial Prostacyclin & cGMP Production (University of Tennessee,
Department of Surgery)
- May 1995 – October 1998
- Medtronic Dynamic Cardiomyoplasty – Skeletal Muscle
Assist Randomized Trial (C-SMART) Phase III (Medtronic, Inc. and Baptist Memorial
Healthcare Foundation)
- May 1995 – April 2001
- A Comparative Assessment of the Hemashield Microvel
Double Velour Vascular Graft vs. the Goretex PTFE Vascular Graft for Above Knee
Femoropopliteal Bypass in Humans (Meadox Medicals, Inc.)
- August 1997 – April 2001
- A Prospective Evaluation of the Meadox VANGUARD
and PASSAGER Endoprostheses for Elective Treatment of Infra-renal Abdominal Aortic
Aneurysms and Aorto-Iliac Aneurysms in Humans (Boston Scientific Corporation, formerly
Meadox Medicals)
- November 1998 – November 2002
- High Risk Protocol: Use Of The VANGUARD and
PASSENGER Endoprostheses For The Elective Treatment of Infra-Renal Abdominal Aortic
Aneurysms And Aorto-Iliac Aneurysms In A Population That Is At High Risk For Open
Surgical Procedures (Boston Scientific Corporation)
- April 2001 – September 2005
- A Long-Term Follow-Up of the Boston Scientific
Medi-tech VANGUARD I and II Endoprosthesis Systems for Elective Treatment of Infra-Renal
Abdominal Aortic Aneurysms and Aorto-Iliac Aneurysms in Humans (Boston Scientific
Corporation)
- January 2000 – September 2001
- A Phase 3, Single-Blind, Randomized, Parallel-Group,
Multicenter, Controlled Study of the Effectiveness of 2.7-g PFC/kg of Perflubron-Based
Emulsion (AF0144) to Augment Intraoperative Autologous Donation and Avoid Transfusion
of Allogeneic Red Blood Cells in Patients Undergoing Primary Coronary Artery Bypass
Graft Surgery under Cardiopulmonary Bypass (Alliance Pharmaceutical Corp., Baptist
Memorial Healthcare Foundation)
- January 2000 – September 2001
- A Randomized, Open-Label Preference Study
of Gengraf Compared to Neoral in Stable Solid-Organ Transplant Subjects (The PREFER
Study)
- March 2001 – December 2001
- ICEM 2000 EMBOL-X Intra-Aortic Filtration System
Clinical Study (Randomized) (EMBOL-X, Inc.)
- September 2000 – December 2001
- A Study of the Safety and Efficacy of TP10
(SCRI) in the Prevention of Post Cardiopulmonary Bypass Syndromes in Adults (Avant
Immunotherapeutics, Inc.)
- July 2001 – July 2002
- A Double-Blind, Placebo-Controlled, Multinational
Trial to Investigate the Effect of IV Treatment with the Na+/H+ Exchange Inhibitor
Cariporide (HOE642) on All-Cause Mortality and Non-fatal Myocardial Infarction in
Patients at Risk of Myocardial Necrosis During and After Coronary Artery Bypass
Graft (CABG) Surgery (Aventis Pharmaceuticals, Inc.)
- May 2002 – December 2003
- Clinical Protocol for a Double-Blind Multicenter
Study of the Safety and Efficacy of Parecoxib Followed by Valdecoxib Compared to
Placebo for Treatment of Post-Surgical Pain in Patients who Have Coronary Bypass
Graft via Median Sternotomy, Protocol #PARA-0505-071 (Pharmacia)
- July 2002 – Closed
- Emergency Use of the TALENT Endoluminal Spring Stent-Graft
System in High Surgical Risk Patients with Abdominal Aortic Aneurysms (Medtronic
Vascular)
- August 2002 - February 2003
- A Phase III Randomized, Parallel, Double-Blind,
Multi-Center, Placebo-Controlled Study of the Effect of Pexelizumab on All-Cause
Mortality and Myocardial Infarction in Patients Undergoing Coronary Artery Bypass
Graft (CABG) Surgery with Cardiopulmonary Bypass, Protocol #2000099 (Alexion Pharmaceuticals,
Inc. and Procter & Gamble Pharmaceuticals)
- April 2003 – September 2007
- Comparison of Primary Patency between GORE-TEX®
PROPATEN Vascular Grafts and Thin Walled GORE-TEX® Stretch Vascular Grafts, PPT
01-04 (W. L. Gore & Associates, Inc.)
- June 2003 – December 2007
- A Non-randomized Clinical Trial of the On-X Prosthetic
Heart Valve vs. the St. Jude Mechanical Valve (Medical Carbon Research Institute)
- November 2003 – 2006
- Destination Therapy Registry (Thoratec)
- December 2003 – August 2005
- TLC-II Home Discharge Registry (Thoratec)
- June 2004 – March 2006
- A Phase 2, Double-Blind, Placebo-Controlled Study
of the Safety and Efficacy of Human Recombinant Soluble Compliment Receptor Type
1 (TP10) in Adult Women Undergoing Cardiopulmonary Bypass Surgery, Protocol #TP10-ACS-002
(Avant Immunotherapeutics, Inc.)
- October 2004 – March 2006
- Multicenter, Randomized, Double-Blind, Parallel-Group,
Placebo-Controlled Study of 2mg/kg Bolus plus 24-Hour 0.05mg/kg Infusion of Pexelizumab
in Patients Undergoing Coronary Artery Bypass Grafting with Cardiopulmonary Bypass
(Alexion Pharmaceuticals, Inc. and Proctor & Gamble Pharmceuticals) (PRIMO)
- September 2005 - March 2006
- Save the Nephron (post heart transplant study)
(Hoffmann-LaRoche, Ltd)
- February 2006 - April 2008
- The HeartMate II LVAS Pivotal Study (Thoratec)
Bridge To Transplant
- April 2006 – 2009
- Positive Impact of Endo Vascular Options for Treating
Aneurysms Early (The PIVOTAL Study) (Medtronic Vascular; The Cleveland Clinic)
- June 2006 – 2008
- MOMENTUM: Multicenter Trial of the Orqis Medical Cardiac
Recovery System for the Enhanced Treatment of CHF Unresponsive to Medical Therapy
(Orqis Medical Corporation)
- June 2006 – 2008
- The EXACT Study – Emboshield and Xact Post Approval Carotid
Stent Trial (Abbott Vascular Devices)
- Dec 2006 – April 2008
- MEND CABG II: A randomized, double-blind, placebo-controlled,
multi-center study to evaluate the cardio protective effects of MC-1 in patients
undergoing high-risk coronary artery bypass graft (CABG) surgery (Medicure International
Inc.)
- March 2007 to 2009
- PEERLESS: Prospective Evaluation of Elastic Restraint
to lessen the Effects of Heart Failure Trial (Paracor)
- August 2007 to October 2007
- Aortic Valve Sixing Clinical Evaluation (Edwards
Life Sciences)
- August 2007- October 2007
- Choice: Carotid Stenting for High Surgical-Risk
Patients; Evaluating Outcomes Through The Collection of Clinical Evidence" (Abbott)